Leuven | More than two weeks ago
Explore the next generation of nanopore sensors at the intersection of bio- and nanotechnology.
The advantageous scalability and density of solid-state nanopore technology can be leveraged for the next generation of biosensors, but several issues still need to be addressed. These include the lack of sensitivity and the high variability of sensitivity of solid-state nanopores. A promising solution is offered by combining a biological nanopore with a solid-state nanopore into a hybrid nanopore, which aims to endow solid-state pores with the high sensitivity of biological nanopores. However, the present hybrid nanopore concepts are encumbered by the engineering at the interface of the biological and solid-state pores, resulting in leakages and misfits.
This topic requires in-depth understanding of experiment and modeling. Diverse hands-on labwork (bio-chemistry, cleanroom, and electrical characterization labs) in addition to state-of-the-art molecular modeling research will be performed.
Required background: Bionanotechnology, Biochemistry, Bio-engineering, Electrical engineering, Physics, or related
Type of work: literature 10%, experimental work 70-20%, modeling 20-70%.
Supervisor: Pol Van Dorpe
Co-supervisor: Anastassia Andreevna Vorobieva
Daily advisor: Koen Martens, Kherim Willems
The reference code for this position is 2025-127. Mention this reference code on your application form.